Natural Product Chemistry: Structure and Biosynthesis of Key Biomolecules

Natural products form the basis of many essential biological processes and are often the starting point for drug discovery. Understanding their complex chemical nature is crucial for advanced chemistry studies. This course provides a comprehensive, text-based foundation in the chemistry of naturally occurring compounds. You will gain the analytical skills necessary to classify, interpret the structure of, and predict the reactions of major biomolecules, setting the stage for advanced research or practical application. What you'll learn: * Understand the classification, stereochemistry, and nomenclature of major natural product families (terpenes, steroids, and alkaloids). * Learn the fundamental reaction mechanisms involved in the synthesis and degradation of carbohydrates and amino acids. * Master the structure and chemical characteristics of peptides and nucleic acids, focusing on primary, secondary, and tertiary structures. * Apply fundamental principles of spectroscopy and chromatography for the structure elucidation and purity assessment of isolated natural compounds. * Practice analyzing basic biosynthetic pathways (such as the acetate and shikimic acid pathways) that lead to complex natural products. The course begins by defining the major classes of natural products and their unique structural features and nomenclature. It then progresses through detailed chemical analysis of each group, covering isolation principles, reaction chemistry, and fundamental biosynthetic routes. This course is designed for absolute beginners in specialized organic chemistry or students seeking a strong conceptual foundation in natural product chemistry. No prior advanced knowledge is required, only basic organic chemistry familiarity. Start building your expertise in the chemistry of life today.