Mobile Genetic Elements: Repeats and Transposons

The majority of the human genome consists of repetitive sequences and mobile elements—yet their function is often misunderstood. This course provides a clear, foundational explanation of these dynamic genomic components, equipping you with the knowledge to understand their profound impact on evolution and disease. This course will teach you how to read and interpret the function of the non-coding and repetitive parts of the genome. What you'll learn: * Understand the classification and mechanisms of action for major classes of mobile genetic elements (DNA transposons and retrotransposons). * Learn how repetitive sequences are identified and characterized in genome sequencing data using foundational bioinformatics concepts. * Apply knowledge of transposon insertion to explain variations in gene structure and regulatory element function. * Analyze the critical role of epigenetic mechanisms, such as DNA methylation, in regulating mobile element activity and maintaining genome stability. * Practice identifying the link between uncontrolled repeat expansion and common genetic diseases and disorders. The course begins with defining key terminology and exploring the history and types of repetitive DNA. It then moves into detailed written explanations of transposition mechanisms, genomic impact, and regulatory control. This course is designed for absolute beginners interested in genetics, biology, or bioinformatics, with no prior knowledge of mobile genetic elements required. Start reading today to unlock the hidden complexity of the human genome.